Osteosarcoma of the Larynx: Treatment Outcomes and Patterns of Failure Analysis
نویسندگان
چکیده
The incidence of laryngeal sarcoma is exceedingly low with osteosarcomas of the larynx being rarer still, comprising less than 1% of all associated malignancies. To date, only 32 cases have been reported since this pathologic entity was first described in 1942. In this article, we discuss the most recent case of laryngeal osteosarcoma in a patient presenting with respiratory distress found to be due to a tumor mass arising from her cricoid cartilage. We further summarize current knowledge regarding the epidemiology, presentation, and diagnosis of this uncommon disease. Lastly, we synthesize all available information regarding treatment and outcomes of the 32 previously described cases of osteosarcoma of the larynx as well as the presently described case in an attempt to offer some insight regarding optimal treatment in future cases.
منابع مشابه
Osteosarcoma of the larynx.
Malignant mesenchymal tumors of the larynx constitute 0.3% to 1% of all laryngeal cancers. Of them, osteosarcoma is the rarest. Osteosarcoma of the larynx may be a difficult clinical diagnosis. Pathologic confirmation of osteoid is required for the diagnosis. Treatment is primarily surgical. It is believed that aggressive surgical intervention directed at complete tumor extirpation is the treat...
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متن کاملOsteosarcomas of the larynx.
OBJECTIVES/HYPOTHESIS The objective was to review the etiology, presentation, treatment, and prognosis in patients with osteosarcoma of the larynx using an illustrative case example. STUDY DESIGN Case report and literature review. METHODS A case is reported, and a review of all available published cases of osteosarcoma of the larynx is presented. RESULTS Osteosarcoma of the larynx may be ...
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